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Structural Biology

68 results.

October 22, 2017 Cryo-EM reveals ignition mechanism for DNA replication

GRAND RAPIDS, Mich. (Oct. 23, 2017) — An international team of scientists, led by scientists at Van Andel Research Institute, Cold Spring Harbor Laboratory and…

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August 1, 2017 How some medications work and how we can make them better

Ever wondered how that daily beta blocker is actually lowering your blood pressure? Or how clopidogrel thins your blood and helps stave off heart attack…

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July 26, 2017 Effects of a major drug target regulated through molecular “codes”

GRAND RAPIDS, Mich. (July 27, 2017)—A team spearheaded by Van Andel Research Institute scientists has answered a long-standing question that may lead to more effective…

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June 28, 2017 Three things to know about prostate cancer this Men’s Health Month

As Men’s Health Month wraps up, here are three important takeaways about prostate cancer, which affects 11 percent of men at some point in their…

June 4, 2017 Research brief: Searching for a crystal-clear picture of a molecular complex linked to cancer, other diseases

Protein: As the workhorses of biology, proteins are involved in virtually every process in the body, from copying the genetic code to digestion.
Receptor:…

February 20, 2017 ORC as Loader of the Rings: Study details ringed structure of ORC in DNA replication

GRAND RAPIDS, Mich. (Feb. 21, 2017)—An international collaboration of life scientists, including experts at Van Andel Research Institute, has described in exquisite detail the…

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January 26, 2017 Copying the genetic code: A quick primer

Sometimes the smallest things have the biggest impact.

A prime example is a recent study from Van Andel Research Institute’s Dr. Huilin…

January 15, 2017 New study reveals the structure of DNA helicase at the replication fork

GRAND RAPIDS, Mich. (Jan. 16, 2017)—Scientists at Van Andel Research Institute and Rockefeller University have successfully described a crucial…