Category:
Carcinomas
Cancer type:
Gastric
Descriptor:
Therapeutic Development
Reference Number:
47
Hirao, S. et al. Tumor suppression effect using NK4, a molecule acting as an antagonist of HGF, on human gastric carcinomas.
Cancer Gene Ther 9, 700-7 (2002).
PubMed link
Reference Number:
48
Morotti, A., Mila, S., Accornero, P., Tagliabue, E. & Ponzetto, C. K252a inhibits the oncogenic properties of Met, the HGF receptor.
Oncogene 21, 4885-93 (2002).
PubMed link
Reference Number:
291
Ueda K, Iwahashi M, Matsuura I, Nakamori M, Nakamura M, Ojima T, Naka T, Ishida K, Matsumoto K, Nakamura T, Yamaue H. Adenoviral-mediated gene transduction of the hepatocyte growth factor (HGF) antagonist, NK4, suppresses peritoneal metastases of gastric cancer in nude mice.
Eur J Cancer 40, 2135-42 (2004)
PubMed link
Reference Number:
313
Ueda K, Iwahashi M, Matsuura I, Nakamori M, Nakamura M, Ojima T, Naka T, Ishida K, Matsumoto K, Nakamura T, Yamaue H. Adenoviral-mediated gene transduction of the hepatocyte growth factor (HGF) antagonist, NK4, suppresses peritoneal metastases of gastric cancer in nude mice.
Eur J Cancer 40, 2135-42 (2004)
PubMed link
Reference Number:
316
Heideman DA, van Beusechem VW, Bloemena E, Snijders PJ, Craanen ME, Offerhaus GJ, Derksen PW, de Bruin M, Witlox MA, Molenaar B, Meijer CJ, Gerritsen WR. Suppression of tumor growth, invasion and angiogenesis of human gastric cancer by adenovirus-mediated expression of NK4.
J Gene Med 6, 317-27 (2004)
PubMed link
Reference Number:
334
Shida D, Kitayama J, Yamaguchi H, Yamashita H, Mori K, Watanabe T, Yatomi Y, Nagawa H. Sphingosine 1-phosphate transactivates c-Met as well as epidermal growth factor receptor (EGFR) in human gastric cancer cells.
FEBS Lett.
577, 333-8 (2004)
PubMed link
Reference Number:
343
Ueda K, Iwahashi M, Matsuura I, Nakamori M, Nakamura M, Ojima T, Naka T, Ishida K, Matsumoto K, Nakamura T, Yamaue H. Adenoviral-mediated gene transduction of the hepatocyte growth factor (HGF) antagonist, NK4, suppresses peritoneal metastases of gastric cancer in nude mice.
Eur J Cancer 40, 2135-42 (2004)
PubMed link
Reference Number:
345
Shinomiya N, Gao CF, Xie Q, Gustafson M, Waters DJ, Zhang YW, Vande Woude GF. RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival.
Cancer Res.
64, 7962-70 (2004)
PubMed link
Reference Number:
667
Perk LR, Stigter-van Walsum M, Visser GW, Kloet RW, Vosjan MJ, Leemans CR, Giaccone G, Albano R, Comoglio PM, van Dongen GA. Quantitative PET imaging of Met-expressing human cancer xenografts with (89)Zr-labelled monoclonal antibody DN30.
Eur J Nucl Med Mol Imaging. 2008 May 20. [Epub ahead of print]
PubMed link
