Our Research

Our Core Services

aaalac accredited Analytical, Cellular, and Molecular Microscopy
(Imaging, Histology and Diagnostic Pathology)

  • Pathology services
  • Tissue Resources
  • Paraffin, frozen and plastic tissue processing
  • Vibratome processing/sectioning
  • Laser capture micro-dissection (Arcturus instrument)
  • Laser scanning confocal imaging (Zeiss 510)
  • Invivo intravital imaging using CRI Maestro
  • Digital imaging
  • Spectral deconvolution imaging

Antibody Production

  • Antibody production
  • Immunization
  • Serum screening
  • Fusion
  • Recloning
  • Characterization
  • Expanding, freezing and growing hybridoma cell lines
  • Purification
  • And more!

Computational Biology 

  • Custom data analysis and consulting
  • Niche program writing
  • Assistance with computationally intensive tasks

Flow Cytometry

  • FACSCalibur
  • FACSAria
  • HTS
  • NPE Cell Analyzer
  • CBC with Differential
  • Blood Chemistry Profile
  • Data Analysis
  • Cytospin

Germline Modification and Cytogenetics  

Mass Spectrometry and Proteomics 

  • Protein expression profiling
  • Protein identification from gels and solution
  • Protein molecular weight determination
  • Protein characterization by peptide mapping

Microarray Technology

  • Agilent Oligonucleotide Gene Expression Microarrays (customizable)
  • ArrayCGH
  • miRNA Expression Microarrays
  • Microarray Data Analysis
  • RNA Isolation and Amplification
  • RNA Integrity Analysis (Agilent Bioanalyzer)
  • DNA isolation and size/concentration analysis
  • Spotted cDNA  Microarray printing
  • Custom Protein Microarray printing

Sequencing

  • Plasmid
  • Single-stranded templates
  • Cosmids/PACs/BACs
  • Lambda phage DNA

Vivarium

Xenotransplantation

  • Over- or underexpress gene(s) in established cell lines to validate their role in the etiology of tumors and their malignant progression
  • Analysis and testing of therapeutics

Michigan Animal Consortium (MAMC)
If you’re looking to outsource mouse modeling services, the Michigan Animal Model Consortium (MAMC) at Van Andel Research Institute (VARI) is ready to become your single point-of-service site for animal model research.