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Van Andel Institute

 

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Van Andel Institute

333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States

March 2019

Robert Roeder, Ph.D. – VARI Seminar Series

March 13, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Mechanisms of transcriptional regulation through diverse co-activators Transcriptional regulation by gene- and cell-specific DNA-binding factors underlies key events in development, cell differentiation and transformation. However, their effects on specific genes depend upon complex arrays of cofactors that include both chromatin modifying factors (e.g., histone acetyl-transferases and methyl-transferases) and other factors (e.g., Mediator and TAFs) that facilitate more direct communication between enhancer-bound regulatory factors and the general transcription machinery. Emphasizing biochemical studies with cell-free systems reconstituted with recombinant chromatin templates and…

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April 2019

David Gilbert, Ph.D. – VARI Seminar Series

April 17, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Regulation of replication timing and chromosome architecture Our goal is to understand how mammalian chromosomes are organized within the nucleus to carry out their functions. DNA replication provides an excellent forum in which to study chromosome structure and function. Structural and functional units of chromosomes replicate coordinately, often through the synchronous firing of clusters of replication origins that encompass domains of approximately 0.5 Mb. Each of these replication domains is programmed to replicate at a specific time during S-phase. In…

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May 2019

Brad Merrill, Ph.D. – VARI Seminar Series

May 1, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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THIS EVENT HAS BEEN CANCELLED.  Novel mechanisms controlling pluripotency of stem cells identified by genome editing approaches The early mammalian embryo traverses remarkably different environments before specification of somatic cell lineages occurs during gastrulation. Transitioning through different states of pluripotency is thought to provide cells a method of accommodating different conditions while they expand in numbers during the embryo’s journey. I will present some of our efforts to elucidate the mechanisms stem cells use to transition between states of pluripotency.…

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Bryan G. Allen, M.D., Ph.D. – VARI Seminar Series

May 15, 2019 @ 12:00 pm - 1:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Manipulating metabolic oxidative stress to enhance cancer therapy Dr. Allen is an assistant professor and physician-scientist in the Department of Radiation Oncology at the University of Iowa. Dr. Allen is a redox biochemist with expertise in manipulating metabolic oxidative stress to enhance radiation and chemotherapy effectiveness and reduce associated treatment related toxicities. He is also a practicing radiation oncologist who participates in developing and running investigator initiated clinical trials. Speaker Information Bryan G. Allen, M.D., Ph.D. Tenure-Track Assistant Professor Department…

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June 2019

Margaret Goodell, Ph.D. – VARI Seminar Series

June 12, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Title TBD Speaker Information Margaret Goodell, Ph.D. Professor and Director, Stem Cells and Regenerative Medicine Center Vivian L. Smith Chair in Regenerative Medicine Co-Leader, Cancer Cell and Gene Therapy Baylor College of Medicine Time & Location 12:00 pm at Van Andel Institute Conference Room 3104/3105 VARI Host: Peter A. Jones, Ph.D., D.Sc. (hon) Questions? For questions, please contact Kim Cousineau at 616.234.5684.

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David Sulzer, Ph.D. – VARI Seminar Series

June 19, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Multiple interactions between dopamine and alpha-synuclein Alpha-synuclein plays an important physiological function by inhibiting the exocytosis of synaptic vesicles but is also plays an instrumental role in the cause of Parkinson’s and additional diseases. We will discuss evidence suggesting how intracellular changes in the handling of this protein may initiate this disease and how it may lead to neuronal death including through steps in the acquired immune system. Speaker Information David Sulzer, Ph.D. Professor Departments of Psychiatry, Neurology, and Pharmacology…

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September 2019

VAI Symposium on Structural Biology

September 12, 2019 - September 13, 2019
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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The Van Andel Research Institute Symposium on Structural Biology will explore the latest advances in the fields of DNA-metabolizing enzymes and membrane proteins. The keynote address will be delivered by Dr. Xiaodong Cheng on Thursday, Sept. 12. A full day of lectures will follow on Friday, Sept. 13.

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Da-Neng Wang, Ph.D. – VAI Seminar Series

September 25, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Title TBD Speaker Information Da-Neng Wang, Ph.D. Professor, Department of Cell Biology NYU Medical School Time & Location 12:00 pm at Van Andel Institute Conference Room 3104/3105 VARI Host: Huilin Li, Ph.D. Questions? For questions, please contact Kim Cousineau at 616.234.5684.

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October 2019

VAI Scientific Vendor Expo

October 1, 2019 @ 10:30 am - 2:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Van Andel Institute is hosting its second annual Scientific Vendor Expo and wants YOU to showcase your company's latest innovations. Join us on Tuesday, October 1, 2019 from 10:30 a.m. – 2:00 p.m. to network with researchers from Van Andel Institute, Michigan State University, Spectrum Health and Grand Valley State University. Attendees  Vendors  The cost is $250 per vendor and includes a table with linen, as well as lunch for the event. Reserve your spot before September 2, 2019 (space…

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Brian Strahl, Ph.D. – VAI Seminar Series

October 23, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Title TBD Speaker Information Brian Strahl, Ph.D. Vice-Chair, Department of Biochemistry and Biophysics University of North Carolina School of Medicine Time & Location 12:00 pm at Van Andel Institute Conference Room 3104/3105 VARI Host: Scott Rothbart, Ph.D. Questions? For questions, please contact Kim Cousineau at 616.234.5684.

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Satdarshan (Paul) Monga, M.D. – VAI Seminar Series

October 30, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Title TBD Speaker Information Satdarshan (Paul) Monga, M.D. Professor of Pathology Professor in Experimental Pathology University of Pittsburgh Time & Location 12:00 pm at Van Andel Institute Conference Room 3104/3105 VARI Host: Postdoctoral Association Questions? For questions, please contact Kim Cousineau at 616.234.5684.

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November 2019

Midwest Metabolism Meeting

November 14, 2019 @ 10:45 am - November 15, 2019 @ 4:30 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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The second Midwest Metabolism Meeting will highlight the latest advances in metabolism research and foster the growth of a collaborative network of scientists from the Midwest. The two-day meeting will kick off with a keynote address from Dr. Julie St.-Pierre from University of Ottawa, who will discuss advances in understanding cancer metastasis and therapeutic resistance using metabolomics. Sessions will delve into tumor metabolism; new advances in immunometabolism and impact on cancer and autoimmune disease; interactions between the metabolome and epigenetic…

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February 2020

Janelle Ayres, Ph.D. – VAI Seminar Series

February 12, 2020 @ 12:00 pm - 1:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Host-microbe interactions: targeting co-evolution to treat disease Speaker Information Janelle Ayres, Ph.D. Professor Molecular and Systems Physiology Lab Gene Expression Laboratory Nomis Center for Immunobiology and Microbial Pathogenesis The Salk Institute for Biological Studies Time & Location 12:00 pm at Van Andel Institute Conference Room 3104/3105 VARI Host: Postdoctoral Association, Emmanuel Quansah, Ph.D. Questions? For questions, please contact Kim Cousineau at 616.234.5684.

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Jerry Workman, Ph.D. – VAI Seminar Series

February 26, 2020 @ 12:00 pm - 1:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Nutritional stress signaling through chromatin Our laboratory has extensive experience in the purification and analysis of protein complexes that modify chromatin for gene expression. This includes both affinity purification techniques and conventional chromatography. Examples of complexes first purified in this laboratory include the SAGA complex from yeast the Tip60 complex from Drosophila and the Sin3 complex from mammalian cells. We have extensively analyzed the mammalian Sin3 deacetylase complexes in collaboration with the Washburn laboratory. We have collaborated extensively with the…

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September 2020

Grand Challenges in Parkinson’s Disease (Virtual)

September 23, 2020 - September 25, 2020
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Grand Challenges in Parkinson’s Disease brings together hundreds of scientists, clinicians and people with Parkinson’s to explore the latest Parkinson’s disease research. The theme for 2020 is When and How Does Parkinson’s Start?, which will focus on the origins and development of Parkinson’s, from potential triggers through the early symptoms and stages of the disease. Van Andel Institute and The Cure Parkinson’s Trust are thrilled to once again host Rallying to the Challenge, a meeting designed for and by people with Parkinson’s,…

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