Cynthia Wolberger, Ph.D. – VAI Seminar Series

Histone ubiquitination in transcription regulation

Speaker Information

Cynthia Wolberger, Ph.D.
Professor of Biophysics and Biophysical Chemistry
The Johns Hopkins University School of Medicine

Abstract/Bio: Cynthia Wolberger is Professor of Biophysics and Biophysical Chemistry at the Johns Hopkins University School of Medicine. Dr. Wolberger received her A.B. in Physics from Cornell University and her Ph.D. in Biophysics from Harvard University, where she did studied the structural basis of protein-DNA interactions. She was a postdoctoral fellow at the University of California, San Francisco and at the Johns Hopkins School of Medicine, where did further research on the structure of homeodomain-DNA complexes. She joined the faculty of the Department of Biophysics and Biophysical Chemistry at the Johns Hopkins School of Medicine in 1991 and was a Howard Hughes Medical Institute Investigator from 1994 – 2014. She is currently department Director and holds the Brown Advisory Colleagues Professorship in Scientific Innovation. Dr. Wolberger has done pioneering work on the structural basis for combinatorial regulation of gene expression, the molecular mechanisms of the sirtuin family of protein deacetylases and on ubiquitin signaling. Her current research focuses on the molecular mechanisms underlying transcription regulation and ubiquitin signaling.

Her contributions have been recognized by the Protein Society’s Dorothy Crowfoot Hodgkin Award and the American Association for Cancer Research Award for Outstanding Achievement in Chemistry in Cancer Research. She is a member of the National Academy of Sciences, the National Academy of Medicine, and the American Academy of Arts and Sciences.

Host: Dr. Evan Worden and the Department of Structural Biology

If you’d like to learn more about Dr. Wolberger and her research, please visit: https://wolberger.med.jhmi.edu/.