Category:
Carcinomas
Cancer type:
Lung
Descriptor:
HGF/SF expression
Reference Number:
88
Eagles, G. et al. Hepatocyte growth factor/scatter factor is present in most pleural effusion fluids from cancer patients.
Br J Cancer 73, 377-81 (1996).
PubMed link
Reference Number:
89
Harvey, P. et al. Immunoreactivity for hepatocyte growth factor/scatter factor and its receptor, met, in human lung carcinomas and malignant mesotheliomas.
J Pathol 180, 389-94 (1996).
PubMed link
Reference Number:
90
Olivero, M. et al. Overexpression and activation of hepatocyte growth factor/scatter factor in human non-small-cell lung carcinomas.
Br J Cancer 74, 1862-8 (1996).
PubMed link
Reference Number:
91
Tsao, M. S., Yang, Y., Marcus, A., Liu, N. & Mou, L. Hepatocyte growth factor is predominantly expressed by the carcinoma cells in non-small-cell lung cancer.
Hum Pathol 32, 57-65. (2001).
PubMed link
Reference Number:
246
Wislez M, Rabbe N, Marchal J, Milleron B, Crestani B, Mayaud C, Antoine M, Soler P, Cadranel J. Hepatocyte growth factor production by neutrophils infiltrating bronchioloalveolar subtype pulmonary adenocarcinoma: role in tumor progression and death.
Cancer Res 63:1405-12 (2003).
PubMed link
Reference Number:
247
Maggiora P, Lorenzato A, Fracchioli S, Costa B, Castagnaro M, Arisio R, Katsaros D, Massobrio M, Comoglio PM, Flavia Di Renzo M. The RON and MET oncogenes are co-expressed in human ovarian carcinomas and cooperate in activating invasiveness.
Exp Cell Res 288:382-9 (2003).
PubMed link
Reference Number:
319
Bharti A, Ma PC, Maulik G, Singh R, Khan E, Skarin AT, Salgia R. Haptoglobin alpha-subunit and hepatocyte growth factor can potentially serve as serum tumor biomarkers in small cell lung cancer.
Anticancer Res 24, 1031-8 (2004
PubMed link
Reference Number:
320
Masuya D, Huang C, Liu D, Nakashima T, Kameyama K, Haba R, Ueno M, Yokomise H. The tumour-stromal interaction between intratumoral c-Met and stromal hepatocyte growth factor associated with tumour growth and prognosis in non-small-cell lung cancer patients.
Br J Cancer 90, 1555-62 (2004)
PubMed link
Reference Number:
369
Yoo MH, Xu XM, Carlson BA, Gladyshev VN, Hatfield DL. Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells.
J Biol Chem. 281, 13005-8 (2006)
PubMed link
Reference Number:
387
Stabile LP, Lyker JS, Land SR, Dacic S, Zamboni BA, Siegfried JM. Transgenic mice overexpressing hepatocyte growth factor in the airways show increased susceptibility to lung cancer.
Carcinogenesis. Mar 2; [Epub ahead of print] (2006)
PubMed link
Reference Number:
394
Hakuma N, Kinoshita I, Shimizu Y, Yamazaki K, Yoshida K, Nishimura M, Dosaka-Akita H. E1AF/PEA3 activates the Rho/Rho-associated kinase pathway to increase the malignancy potential of non-small-cell lung cancer cells.
Cancer Res. 65, 10776-82 (2005)
PubMed link
Reference Number:
395
Sugimoto T, Takiguchi Y, Kurosu K, Kasahara Y, Tanabe N, Tatsumi K, Hiroshima K, Minamihisamatsu M, Miyamoto T, Kuriyama T. Growth factor-mediated interaction between tumor cells and stromal fibroblasts in an experimental model of human small-cell lung cancer.
Oncol Rep. 14, 823-30 (2005)
PubMed link
Reference Number:
438
Chen JT, Lin TS, Chow KC, Huang HH, Chiou SH, Chiang SF, Chen HC, Chuang TL, Lin TY, Chen CY. Cigarette smoking induces overexpression of hepatocyte growth factor in type II pneumocytes and lung cancer cells.
Am J Respir Cell Mol Biol. 34, 264-73 (2006)
PubMed link
Reference Number:
570
Nakamura Y, Niki T, Goto A, Morikawa T, Miyazawa K, Nakajima J, Fukayama M. c-Met activation in lung adenocarcinoma tissues: an immunohistochemical analysis.
Cancer Sci.
98, 1006-13 (2007)
PubMed link
Reference Number:
601
Chen JT, Huang CY, Chiang YY, Chen WH, Chiou SH, Chen CY, Chow KC. HGF Increases Cisplatin Resistance via Down-Regulation of AIF in Lung Cancer Cells.
Am J Respir Cell Mol Biol. 38, 559-65 (2008)
PubMed link
Reference Number:
602
Pierce A, Barron N, Linehan R, Ryan E, O'Driscoll L, Daly C, Clynes M. Identification of a novel, functional role for S100A13 in invasive lung cancer cell lines.
Eur J Cancer.
44, 151-9 (2008)
PubMed link
Reference Number:
692
Yano S, Wang W, Li Q, Matsumoto K, Sakurama H, Nakamura T, Ogino H, Kakiuchi S, Hanibuchi M, Nishioka Y, Uehara H, Mitsudomi T, Yatabe Y, Nakamura T, Sone S. Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations.
Cancer Res.
68, 9479-87 (2008)
PubMed link
