Clinical Trials and Participating Hospitals

support neuroblastoma research We are actively recruiting for specific clinical studies. Click on a specific study for more information. If you are interested in participating in one of the trials below, please contact Genevieve Bergendahl at 616-234-5707 or via email, or one of the contacts at the hospitals below.

Phase

NMTRC#

Trial Name Status
Phase II

V0706

Nifurtimox to Treat Refractory or Relapsed Neuroblastoma or Medulloblastoma Open
Phase I 

NMTRC 001

Molecular Guided Therapy for Refractory or Recurrent Neuroblastoma  Open
Phase I NMTRC 002 DFMO alone and in combination with Etoposide for Relapsed or Refractory Neuroblastoma  Open
Phase II NMTRC 003 Preventative Trial of DFMO in Patients With High Risk Neuroblastoma in Remission  Pending
Phase I/II NMTRC 004 Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastoma  Open
Phase I/II NMTRC 005 Randomized Efficacy Study of TPI 287 to Treat Primary Refractory or Early Relapsed Neuroblastoma  Open
Compassionate Use NMTRC 006 A Compassionate Use Trial of DFMO as a Single Agent Pending
Biology NMTRC 00B A Molecular Analysis of Pediatric Tumors with Establishment of Tumor Models and a Tissue Biology Study Open
Phase I TPI-287-11 TPI 287 as a Single Agent and in Combination With Temozolomide in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma Completed
Pilot NMTRC001P Feasibility of Using Molecular-Guided Therapy in Patients With Refractory or Recurrent
Neuroblastoma
 
Completed
Phase I V0610 Nifurtimox for Relapsed or Refractory Neuroblastoma Completed

Participating Hospitals

Please contact the appropriate person below for further information on NMTRC clinical trials offered at each hospital site.

van andel institute

helen devos children's hospital

Giselle Sholler, MD and Deanna Mitchell, MD

Van Andel Research Institute
333 Bostwick Avenue NE
Grand Rapids, MI  49503
Tel: (616) 234-5495
Helen DeVos Children's Hospital
Michigan State University
100 Michigan NE
Grand Rapids, MI 49503
Tel: (616) 391-2086
Email: Dr. Sholler
Email: Deanna.Mitchell@devoschildrens.org

cardinal glennon children's medical center

William Ferguson, MD
Cardinal Glennon Children's Medical Center
Saint Louis University School of Medicine
1465 S. Grand Blvd.
Saint Louis, MO 63104
Tel: (314) 577-5638
Email: fergusws@slu.edu

rady children's hospital san diego

William Roberts, MD
Rady Children's Hospital San Diego
UCSD School of Medicine
3020 Children's Way
MC5035
San Diego, CA 92123-4282
Tel: (858) 966-5811
Email: wroberts@chsd.org

arnold palmer hospital for children

Don Eslin, MD
Center for Children's Cancer and Blood Disorders
Arnold Palmer Hospital for Children
M.D. Anderson Cancer Center Orlando
92 West Miller St., MP318
Orlando, FL 32806
Tel: 321-841-8588
Email: Don.Eslin@orlandohealth.com

musc

Jacqueline M Kraveka, DO
Medical University of South Carolina
135 Rutledge Avenue, Room 480
MSC 558
Charleston, SC 29425
Tel: (843) 792-2957
Email: kravekjm@musc.edu

levine children's hospital

Joel Kaplan, DO, MPH
Levine Children's Hospital
1001 Blythe Blvd
Charlotte, NC 28203
Tel: (704) 381-9900
Email: Joel.Kaplan@carolinashealthcare.org

connecticut children's medical center

Nehal S. Parikh, MD
Connecticut Children's Medical Center
Division of Hematology/Oncology 2J
282 Washington Street
Hartford, CT 06106
Tel: (860) 545-9630
Email: nparikh@ccmckids.org

 children's mercy hospitals and clinics kansas city

Kathleen A. Neville, M.D., M.S.
Children's Mercy Hospitals and Clinics
Divisions of Pediatric Clinical Pharmacology and Pediatric Hematology/Oncology
2401 Gillham Road
Kansas City, MO 64108
Tel: 816-234-3059
Email: kaneville@cmh.edu

national cancer institute

Melinda S. Merchant, MD, PhD
National Cancer Institute
Center for Cancer Research
Pediatric Oncology Branch
Staff Clinician
10 Center Dr
Bldg 10 CRC, Room 1W-3840
Bethesda, MD 20892
Tel: 301-443-7955
Email: merchanm@mail.nih.gov

vanderbilt-ingram cancer center

Valerie I. Brown, MD, PhD
Assistant Professor of Pediatrics
Vanderbilt-Ingram Cancer Center
397 Preston Research Building
2220 Pierce Ave
Nashville, TN 37232
Tel: 615-875-6129
Email: valerie.brown@vanderbilt.edu

phoenix children's hospital

Francis Eshun, MD
Center for Cancer and Blood Disorders
Phoenix Children's Hospital
1919 Thomas Road
Phoenix, AZ 85016
Email: feshun@phoenixchildrens.com

dell children's medical center of central texas

Sharon K Lockhart, MD
COG Principal Investigator
Clinical Research Director,
Dell Children's Blood and Cancer Center
1301 Barbara Jordan Blvd, Ste 401
Austin,  Texas   78723
Tel: 512-628-1900
Email: slockhart@sfcaustin.com

primary children's medical center

Mark Fluchel, MD
Primary Children's Hospital
Division of Pediatric Hematology/Oncology
100 North Mario Capecchi Drive, 4th Floor
Salt Lake City, UT 84113
Tel: 801-662-4700
Email: markfluchel@imail.org

our team