Williams, Bart, Ph.D. Associate Professor and Director, Center for Skeletal Disease Research; Head, Laboratory of Cell Signaling and Carcinogenesis
Phone: 616-234-5308 Fax: 616-234-5309
Biographical Sketch and Selected Publications E-Mail Staff Head E-Mail Lab
Staff Zylstra-Diegel, Cassandra, B.S. Lewis, Diana Mowry, Laura, B.S. Schumacher, Cassie, B.S. Less, Kennen, B.S. Snider, John, B.S.
Postdoctoral Fellows Burgers, Travis, Ph.D. Joiner, Danese, Ph.D. Zhong, Alex, Ph.D.
Students Droscha, Casey, B.S. Spiering, Tyler Valkenburg, Ken, B.S. Van Wieren, Emily
Adjunct Faculty Jones, Clifford, M.D. Sietsema, Debra, Ph.D.
Scientific Overview
General Overview
Bart Williams and his lab staff study the Wnt family of proteins and their associated molecules. Wnt proteins are remarkably similar in species ranging from nematodes (parasitic worms) to vertebrate animals, and changes in the signaling pathway of Wnt proteins is one of the most common cellular changes associated with cancer, as well as other disorders such as osteoporosis. The lab’s researchers are studying the cellular receptors for Wnt molecules, the effects of mutations on Wnt signaling, and the role of Wnt proteins in melanoma and prostate cancer.
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