Han-Mo Koo Seminar Series

Speaker: Donald J. Tindall, Ph.D.
VAI Host:  Miranti , Cindy, Ph.D.
Speaker Affiliation: Mayo Clinic Foundation and Mayo Clinic College of Medicine
Speaker Title: Vice-Chair of Urology Research and Professor, Department of Biochemistry and Molecular Biology, Director/Professor, Department of Urology Research, Consultant, Department of Urology
Date: June 4, 2008
Time: 12:00 PM to 1:00 PM
Location: Van Andel Institute - Tomatis Auditorium

The Tindall Lab is studying prostate cancer and the mechanisms by which prostate cancer cells survive following androgen ablation, the most common therapy for advanced prostate cancer. We are testing the hypothesis that the androgen receptor plays a key role in androgen-independent prostate cancer following androgen ablation therapy. We are studying the molecular mechanisms by which co-regulatory proteins modulate the transcriptional activity of the androgen receptor and how these proteins are altered in prostate cancer.

We are also studying the downstream targets of the androgen receptor that are involved in cell proliferation and cell death. We are focusing on the mechanisms by which Forkhead transcription factors are regulated by androgens and how this affects proliferation and apoptosis in prostate cancer cells. We anticipate that our research will identify cellular targets for detection, prognosis, prevention, and treatment of prostate cancer.

In person attendance.

Van Andel Research Institute
Tomatis Auditorium
333 Bostwick Ave., N.E.
Grand Rapids, Michigan
49503

Online viewing.

Via webcast* at http://media.vai.org/vaichannel2
Windows Media Player version 9 or above and at least 300Kbps of Internet bandwidth will be required.

*Participants viewing this webcast are not currently eligible for CME Accreditation; however, the Michigan State Medical Society is currently reviewing this process

“This activity has been planned and implemented in accordance with the Essential Areas and policies of the Michigan State Medical Society Committee on CME Accreditation through the joint sponsorship of the Grand Rapids Medical Education & Research Center for Health Professions and the Van Andel Research Institute. The Grand Rapids Medical Education & Research Center for Health Professions is accredited by the Michigan State Medical Society Committee on CME Accreditation to provide continuing medical education for physicians. The Grand Rapids Medical Education & Research Center for Health Professions designates this educational activity for a maximum of one Category 1 credit toward the AMA Physician’s Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.”

For more information please contact Laura Holman at (616) 234-5749